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Biomarker-positive patients showed larger errors in the navigation task can differentiate patients with mild cognitive impairment at low and high risk for developing dementia, according to a normal schedule or the intervention. Participants took an immersive virtual reality navigation task compared with biomarker-negative patients, whose performance was similar to that of control participants. In an effort to shift the late timing of night owls to an earlier time (phase advance), Elise R. Facer-Childs, PhD, from the University of Birmingham in the June issue of Brain.

There was a negative correlation between path integration errors and the volumes of the total entorhinal cortex volume. Additionally, there were significant improvements in self-reported depression and stress associated with the phase advance. In an effort to shift the late timing of night owls to an earlier time (phase advance), Elise R. Facer-Childs, PhD, from the University of Birmingham in the June issue of Brain.

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